Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.82 |
| ▸ | MAPT | P10636 | 8/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | RECQL | P46063 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | ESR1 | P03372 | 1/20 | 0.72 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.72 |
| ▸ | BAP1 | Q92560 | 1/20 | 0.72 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | TNF | P01375 | 1/20 | 0.62 |
| ▸ | CRHBP | P24387 | 1/20 | 0.62 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.62 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.62 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17130651 | 0.82 | MAPT (0.81) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL19425600 | 0.80 | L3MBTL1 (0.76) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL17130736 | 0.73 | MAPT (0.78) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL17624905 | 0.72 | MAPT (0.74) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL6721061 | 0.70 | KMT2A (0.76) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL17130743 | 0.70 | POLB (0.61) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL17130737 | 0.69 | SMN1; SMN2 (0.66) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL30444288 | 0.69 | MMP9 (1.00) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL17130734 | 0.68 | KLK7 (0.73) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL19420129 | 0.68 | ALDH1A1 (0.71) | ALDH1A1MAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9216180-B2 | Pharmaceutical compositions and treatment of genetic diseases associated with nonsense mediated RNA decay | NEW YORK UNIVERSITY (US) | 2015-12-22 | — | — | US | disclosed |