SCHEMBL17355696

SCHEMBL17355696

Cc1cc(OS(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)ccc1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
KMT2A Q03164 3/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.37
PTGS2 P35354 4/20 0.36
STS P08842 1/20 0.36
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36
PTGS1 P23219 2/20 0.35
TSHR P16473 2/20 0.35
ESR1 P03372 1/20 0.35
ATM Q13315 1/20 0.35
ESR2 Q92731 1/20 0.35
EPAS1 Q99814 2/20 0.34
HTR2A P28223 1/20 0.34
SLC6A4 P31645 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17355688 0.85 KMT2A (0.54) CA1CA2KMT2AMAPTMEN1
SCHEMBL17355677 0.79 PTGS2 (0.39) CA1CA2KMT2ASMN1; SMN2POLB
SCHEMBL7247499 0.79 ALDH1A1 (0.49) CA2KMT2ASMN1; SMN2PTGS2PTGS1
SCHEMBL17355689 0.79 KMT2A (0.55) CA2KMT2AMAPTMEN1SMN1; SMN2
SCHEMBL17355694 0.79 KMT2A (0.46) KMT2AMEN1SMN1; SMN2LMNAPTGS2
SCHEMBL17355680 0.79 TDP1 (0.56) CA2KMT2AMAPTMEN1SMN1; SMN2
SCHEMBL17355692 0.79 AKR1C3 (0.47) CA2KMT2AMEN1SMN1; SMN2LMNA
SCHEMBL17356435 0.78 CA1 (0.44) CA1CA2STSHTR2ASLC6A4
SCHEMBL17355690 0.78 KMT2A (0.52) KMT2AMAPTMEN1SMN1; SMN2LMNA
SCHEMBL17355682 0.76 ALDH1A1 (0.39) KMT2AMEN1SMN1; SMN2POLBPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE HCN2, SCO2, HCN1 CA1 1448/4885CA2 286/4885KMT2A 2355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.