SCHEMBL17356136

SCHEMBL17356136

COc1ccc2ccccc2c1-c1c(Oc2ccc(C(=O)c3ccc(C)cc3)cc2)ccc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.56
ALDH1A1 P00352 5/20 0.47
SMN1; SMN2 Q16637 4/20 0.47
LMNA P02545 4/20 0.47
KMT2A Q03164 4/20 0.45
MEN1 O00255 2/20 0.45
TTR P02766 1/20 0.44
HTT P42858 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
GAA P10253 1/20 0.43
RAB9A P51151 1/20 0.42
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
MAPK1 P28482 1/20 0.41
HPGD P15428 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17879944 0.95 MAPT (0.51) MAPTALDH1A1SMN1; SMN2LMNAKMT2A
SCHEMBL17879945 0.91 MAPT (0.47) MAPTALDH1A1SMN1; SMN2LMNAKMT2A
SCHEMBL17879938 0.88 MAPT (0.44) MAPTALDH1A1SMN1; SMN2LMNAKMT2A
SCHEMBL17879942 0.87 MAPT (0.42) MAPTALDH1A1SMN1; SMN2LMNAKMT2A
SCHEMBL9914255 0.85 MAPT (0.52) MAPTALDH1A1SMN1; SMN2LMNAKMT2A
SCHEMBL17356140 0.82 MAPT (0.56) MAPTALDH1A1SMN1; SMN2LMNAKMT2A
SCHEMBL822937 0.82 ALDH1A1 (0.53) MAPTALDH1A1SMN1; SMN2LMNAKMT2A
SCHEMBL13374189 0.81 L3MBTL1 (0.61) MAPTALDH1A1LMNAKMT2AMEN1
SCHEMBL10093724 0.81 L3MBTL1 (0.61) MAPTALDH1A1LMNAKMT2AMEN1
SCHEMBL17356141 0.80 MAPT (0.54) MAPTALDH1A1SMN1; SMN2LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9601325-B2 Aromatic resins for underlayers ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2017-03-21 US disclosed
US-9508549-B2 Methods of forming electronic devices including filling porous features with a polymer DOW GLOBAL TECHNOLOGIES LLC (US) 2016-11-29 US disclosed
US-20160185984-A1 PORE-FILL COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2016-06-30 US disclosed
US-20160189953-A1 METHODS OF FORMING ELECTRONIC DEVICES ROHM AND HAAS ELECTRONIC MATERIALS LLC 2016-06-30 US disclosed
US-20150368504-A1 AROMATIC RESINS FOR UNDERLAYERS ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) 2015-12-24 US disclosed