SCHEMBL17356141

SCHEMBL17356141

COc1ccc2ccccc2c1-c1c(Oc2ccc(C(O)(c3ccccc3)c3ccc(C)cc3)cc2)ccc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.54
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
NISCH Q9Y2I1 1/20 0.39
HPGD P15428 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP2D6 P10635 1/20 0.39
HIF1A Q16665 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALDH1A1 P00352 2/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
KIF11 P52732 3/20 0.37
KDM4E B2RXH2 1/20 0.36
MAPK1 P28482 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
HTT P42858 1/20 0.36
AR P10275 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17356136 0.80 MAPT (0.56) MAPTMEN1KMT2AHPGDCYP1A2
SCHEMBL17356140 0.80 MAPT (0.56) MAPTMEN1KMT2ANISCHHPGD
SCHEMBL17879945 0.80 MAPT (0.47) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL18383296 0.79 KIF11 (0.37) MAPTMEN1KMT2AHPGDCYP1A2
SCHEMBL17879938 0.77 MAPT (0.44) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL17879944 0.76 MAPT (0.51) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL12199475 0.75 KIF11 (0.56) RAB9ASMN1; SMN2KIF11HTTAHR
SCHEMBL18383300 0.75 KIF11 (0.34) MAPTMEN1KMT2AHPGDCYP1A2
SCHEMBL18383304 0.74 KIF11 (0.37) MEN1KMT2AHPGDCYP1A2CYP2C9
SCHEMBL18383303 0.74 GPR84 (0.35) MAPTKIF11L3MBTL1AHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9601325-B2 Aromatic resins for underlayers ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2017-03-21 US disclosed
US-20150368504-A1 AROMATIC RESINS FOR UNDERLAYERS ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) 2015-12-24 US disclosed