Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.39 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 4/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21887849 | 0.83 | ELOVL1 (0.38) | ELOVL1CASRKDM4E | |
| SCHEMBL23368131 | 0.83 | ELOVL1 (0.40) | ELOVL1RXRAGRIN1GRIN2BCASR | |
| SCHEMBL21805818 | 0.83 | CASR (0.34) | RXRAGRIN1GRIN2BCASRKCNH2 | |
| SCHEMBL15935038 | 0.81 | RAB9A (0.47) | ELOVL1UHRF1RXRAGRIN1GRIN2B | |
| SCHEMBL22041242 | 0.81 | RAB9A (0.41) | ELOVL1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL17356153 | 0.79 | AR (0.43) | RXRAGRIN1GRIN2BCASR | |
| SCHEMBL23176116 | 0.78 | CASR (0.40) | ELOVL1IRAK4PDE10ACASRHTT | |
| SCHEMBL15980626 | 0.77 | NOTUM (0.40) | PDE10ACASRKDM4EALDH1A1GAA | |
| SCHEMBL15924047 | 0.77 | ELOVL1 (0.40) | ELOVL1UHRF1RXRAGRIN1GRIN2B | |
| SCHEMBL20242276 | 0.77 | ELOVL1 (0.40) | ELOVL1UHRF1RXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9695198-B2 | Factor IXa inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-07-04 | — | — | US | disclosed |
| US-20150368269-A1 | Factor IXa Inhibitors | MERCK SHARP & DOHME CORP. (US) | 2015-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150368269-A1 | Factor IXa Inhibitors | F9, TFPI, F13B | ELOVL1 4187/4885UHRF1 4344/4885RXRA 701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.