SCHEMBL17356307

SCHEMBL17356307

CCCS(=O)(=O)Oc1ccc(F)c(C(F)(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.41
CA2 P00918 2/20 0.41
MMP2 P08253 2/20 0.40
MMP9 P14780 2/20 0.40
MMP14 P50281 2/20 0.40
MMP7 P09237 1/20 0.40
HTR2A P28223 1/20 0.40
SLC6A4 P31645 1/20 0.40
KCNH2 Q12809 1/20 0.40
PTPN7 P35236 1/20 0.39
DUSP3 P51452 1/20 0.39
CNR2 P34972 3/20 0.38
MEN1 O00255 1/20 0.37
CNR1 P21554 1/20 0.37
GPR183 P32249 1/20 0.37
KMT2A Q03164 1/20 0.37
ENPP3 O14638 1/20 0.37
ENPP1 P22413 1/20 0.37
ENPP2 Q13822 1/20 0.37
SLC22A12 Q96S37 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17356303 0.92 ALPL (0.44) CA12CA2HTR2ASLC6A4KCNH2
SCHEMBL17356304 0.89 HTR2A (0.42) CA12CA2MMP2MMP9MMP14
SCHEMBL17356440 0.82 CNR2 (0.39) CA2HTR2ASLC6A4KCNH2PTPN7
SCHEMBL17355674 0.80 CA12 (0.44) CA12CA2MMP2MMP9MMP14
SCHEMBL17352133 0.80 ALDH1A1 (0.53) CA2HTR2ASLC6A4KCNH2SLC22A12
SCHEMBL17356299 0.78 SLC22A12 (0.42) CA2HTR2ASLC6A4KCNH2SLC22A12
SCHEMBL17356301 0.78 HTR2A (0.36) HTR2ASLC6A4KCNH2PTPN7DUSP3
SCHEMBL17356302 0.78 SLC22A12 (0.41) CA2HTR2ASLC6A4KCNH2PTPN7
SCHEMBL17356309 0.78 HTR1D (0.43) CA2HTR2ASLC6A4KCNH2SLC22A12
SCHEMBL17356308 0.77 HTR2A (0.38) HTR2ASLC6A4KCNH2PTPN7DUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE HCN2, SCO2, HCN1 CA12 2756/4885CA2 286/4885MMP2 3717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.