SCHEMBL17356397

SCHEMBL17356397

CS(=O)(=O)Oc1c(F)c(F)c(C(F)(F)F)c(F)c1F

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.43
TSHR P16473 1/20 0.43
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28860791 0.96 CA1 (0.42) SMN1; SMN2TSHRCA1CA2CA9
SCHEMBL585314 0.82 CA1 (0.56) TSHRCA1CA2CA9
SCHEMBL4345099 0.78 CA1 (0.46) TSHRCA1CA2CA9
SCHEMBL9957855 0.76 CA1 (0.44) TSHRCA1CA2CA9
SCHEMBL17355703 0.76 CA1 (0.44) TSHRCA1CA2CA9KMT2A
SCHEMBL28988340 0.74 CA1 (0.48) CA1CA2CA9
SCHEMBL9957399 0.72 CA1 (0.46) TSHRCA1CA2CA9
SCHEMBL28859552 0.72 KIF11 (0.37) CA1CA2CA9ALDH1A1
SCHEMBL13488483 0.71 CA1 (0.40) CA1CA2CA9ALDH1A1
SCHEMBL15453710 0.71 KIF11 (0.36) CA1CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE HCN2, SCO2, HCN1 SMN1; SMN2 3445/4885TSHR 3426/4885CA1 1448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.