SCHEMBL17356798

SCHEMBL17356798

CC1CCCCC1c1ccccc1C(F)(F)F

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.51
TDP1 Q9NUW8 1/20 0.51
HTR2C P28335 3/20 0.47
HTR2B P41595 1/20 0.47
TAS1R3 Q7RTX0 2/20 0.44
TAS1R1 Q7RTX1 2/20 0.44
TAS1R2 Q8TE23 2/20 0.44
PNMT P11086 1/20 0.41
RBP4 P02753 5/20 0.40
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
CUL4A Q13619 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17356804 0.97 HTR2C (0.47) GAATDP1HTR2CHTR2BTAS1R3
SCHEMBL17356806 0.89 HTR2C (0.50) GAATDP1HTR2CHTR2BPNMT
SCHEMBL24005938 0.85 HTR2C (0.40) GAATDP1HTR2CHTR2BTAS1R3
SCHEMBL17356801 0.84 HTR2C (0.49) GAATDP1HTR2CHTR2BTAS1R3
SCHEMBL12875533 0.82 HTR2C (0.57) GAATDP1HTR2CHTR2BPNMT
SCHEMBL31172489 0.82 HTR2C (0.57) GAATDP1HTR2CHTR2BPNMT
Ammonia Solution, Strong SCHEMBL267014 0.80 HTR2C (0.56) GAATDP1HTR2CHTR2BPNMT
SCHEMBL21451906 0.79 GAA (0.55) GAATDP1HTR2CHTR2BPNMT
SCHEMBL17356796 0.78 HTR2C (0.43) GAATDP1HTR2CHTR2BPNMT
SCHEMBL17356809 0.77 PNMT (0.46) GAATDP1HTR2CHTR2BTAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170313792-A1 METHOD FOR PRODUCING POLAR GROUP-CONTAINING OLEFIN POLYMER THE UNIVERSITY OF TOKYO (JP) 2017-11-02 US disclosed
US-9499644-B2 Production method of polar group-containing olefin polymers SHOWA DENKO K.K. (JP) 2016-11-22 US disclosed
US-20150368376-A1 PRODUCTION METHOD OF POLAR GROUP-CONTAINING OLEFIN POLYMERS SHOWA DENKO K.K. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150368376-A1 PRODUCTION METHOD OF POLAR GROUP-CONTAINING OLEFIN POLYMERS OR10J3, OPRM1, ORC3 GAA 4719/4885TDP1 4736/4885HTR2C 2694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.