SCHEMBL17356809

SCHEMBL17356809

CC1CCCC1c1c(C(F)(F)F)cccc1C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.46
TAS1R3 Q7RTX0 3/20 0.45
TAS1R1 Q7RTX1 3/20 0.45
TAS1R2 Q8TE23 3/20 0.45
CHRNB2 P17787 1/20 0.39
CHRNA4 P43681 1/20 0.39
HTR2C P28335 3/20 0.35
GAA P10253 2/20 0.35
HTR2B P41595 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
AR P10275 2/20 0.35
SLC6A2 P23975 3/20 0.34
SLC6A4 P31645 3/20 0.34
GRM2 Q14416 1/20 0.34
SCN9A Q15858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17356808 0.89 PNMT (0.53) PNMTTAS1R3TAS1R1TAS1R2CHRNB2
SCHEMBL17356789 0.87 TAS1R3 (0.44) PNMTTAS1R3TAS1R1TAS1R2CHRNB2
SCHEMBL17356804 0.81 HTR2C (0.47) PNMTTAS1R3TAS1R1TAS1R2HTR2C
SCHEMBL17356805 0.78 PNMT (0.43) PNMTTAS1R3TAS1R1TAS1R2CHRNB2
SCHEMBL17356798 0.77 GAA (0.51) PNMTTAS1R3TAS1R1TAS1R2HTR2C
SCHEMBL13632697 0.75 PNMT (0.49) PNMTCHRNB2CHRNA4HTR2CGAA
SCHEMBL24005938 0.72 HTR2C (0.40) PNMTTAS1R3TAS1R1TAS1R2HTR2C
SCHEMBL13826207 0.72 ESR1 (0.45) HTR2CHTR2B
SCHEMBL17356803 0.71 PNMT (0.43) PNMTTAS1R3TAS1R1TAS1R2CHRNB2
SCHEMBL17356802 0.71 PNMT (0.38) PNMTTAS1R3TAS1R1TAS1R2CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170313792-A1 METHOD FOR PRODUCING POLAR GROUP-CONTAINING OLEFIN POLYMER THE UNIVERSITY OF TOKYO (JP) 2017-11-02 US disclosed
US-9499644-B2 Production method of polar group-containing olefin polymers SHOWA DENKO K.K. (JP) 2016-11-22 US disclosed
US-20150368376-A1 PRODUCTION METHOD OF POLAR GROUP-CONTAINING OLEFIN POLYMERS SHOWA DENKO K.K. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150368376-A1 PRODUCTION METHOD OF POLAR GROUP-CONTAINING OLEFIN POLYMERS OR10J3, OPRM1, ORC3 PNMT 316/4885TAS1R3 1857/4885TAS1R1 2747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.