SCHEMBL17358749

SCHEMBL17358749

CCCCC1C(=O)N(Cc2ccccc2)C(=O)N(Cc2ccccc2)C1=O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 2/20 0.64
ELANE P08246 3/20 0.55
F2 P00734 1/20 0.55
PLG P00747 1/20 0.55
CTSG P08311 1/20 0.55
CMA1 P23946 1/20 0.55
CTRC Q99895 1/20 0.55
ALDH1A1 P00352 8/20 0.52
KMT2A Q03164 4/20 0.52
MEN1 O00255 3/20 0.52
CYP3A4 P08684 4/20 0.50
MAPT P10636 3/20 0.50
CYP1A2 P05177 3/20 0.50
CYP2C9 P11712 3/20 0.50
CYP2C19 P33261 3/20 0.50
LMNA P02545 1/20 0.50
MAPK1 P28482 1/20 0.50
TP53 P04637 1/20 0.50
HPGD P15428 1/20 0.50
PTGS1 P23219 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15978111 0.89 EP300 (0.51) EP300ELANEF2PLGCTSG
SCHEMBL17717959 0.83 ALDH1A1 (0.47) EP300ELANEF2PLGCTSG
SCHEMBL16859923 0.82 KMT2A (0.51) EP300ELANEALDH1A1KMT2AMEN1
SCHEMBL15978132 0.81 EP300 (0.42) EP300CMA1ALDH1A1KMT2AMEN1
SCHEMBL18344440 0.79 ALDH1A1 (0.46) EP300ELANEF2PLGCTSG
SCHEMBL15131570 0.78 EP300 (1.00) EP300ELANEF2PLGCTSG
SCHEMBL17358741 0.76 ELANE (0.67) EP300ELANEF2PLGCTSG
SCHEMBL1426468 0.76 ELANE (0.48) ELANEF2CTSGCTRCALDH1A1
SCHEMBL31681885 0.74 SMN1; SMN2 (0.43) ELANEF2CTSGCTRCALDH1A1
SCHEMBL14560433 0.74 ELANE (0.58) EP300ELANEF2PLGCTSG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9551813-B2 Optical film, polarizing plate using same, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-01-24 US disclosed
US-9551813-B2 Optical film, polarizing plate using same, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-01-24 US disclosed
US-20150369960-A1 OPTICAL FILM, POLARIZING PLATE USING SAME, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-12-24 US disclosed
US-20150369960-A1 OPTICAL FILM, POLARIZING PLATE USING SAME, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-12-24 US disclosed