Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.52 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.52 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.52 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8051170 | 0.93 | GSTO1 (0.46) | PDK2PDK1PDK3PDK4SMN1; SMN2 | |
| SCHEMBL11886812 | 0.88 | GAA (0.45) | PDK2PDK1PDK3PDK4SMN1; SMN2 | |
| SCHEMBL8061101 | 0.86 | SMN1; SMN2 (0.44) | PDK2PDK1PDK3PDK4SMN1; SMN2 | |
| SCHEMBL8067688 | 0.85 | TSHR (0.42) | PDK2PDK1PDK3PDK4SMN1; SMN2 | |
| SCHEMBL11886827 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL8062228 | 0.84 | GSTO1 (0.48) | SMN1; SMN2ALDH1A1LMNAKDM4EGSTO1 | |
| SCHEMBL8067685 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL8054565 | 0.82 | POLB (0.47) | SMN1; SMN2ALDH1A1LMNAKDM4EKMT2A | |
| SCHEMBL8062230 | 0.81 | TSHR (0.51) | SMN1; SMN2ALDH1A1LMNAKDM4EGSTO1 | |
| SCHEMBL18434303 | 0.79 | ALDH1A1 (0.42) | PDK2SMN1; SMN2ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150366977-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING NITROXYL DONORS | CARDIOXYL PHARMACEUTICALS, INC. | 2015-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150366977-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING NITROXYL DONORS | TNNT2, TNNI3, NQO1 | PDK2 1195/4885PDK1 1409/4885PDK3 1319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.