Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17359592 | 1.00 | LMNA (0.33) | LMNAPRKCATSHRTDP1L3MBTL1 | |
| SCHEMBL17359834 | 0.89 | ABCB1 (0.31) | ABCB1 | |
| SCHEMBL17359833 | 0.89 | ABCB1 (0.31) | ABCB1 | |
| SCHEMBL18877289 | 0.82 | ABCB1 (0.30) | ABCB1 | |
| SCHEMBL17359605 | 0.80 | ABCB1 (0.41) | LMNAPRKCATSHRTDP1L3MBTL1 | |
| SCHEMBL16144614 | 0.73 | ALDH1A1 (0.33) | LMNAPRKCATSHRTDP1ALDH1A1 | |
| SCHEMBL18721439 | 0.71 | ALDH1A1 (0.33) | LMNAPRKCATSHRTDP1ALDH1A1 | |
| SCHEMBL17863951 | 0.68 | MAPT (0.35) | PRKCAABCB1 | |
| SCHEMBL17359828 | 0.67 | ABCB1 (0.40) | ABCB1 | |
| SCHEMBL17359596 | 0.66 | ABCB1 (0.33) | TSHRTDP1L3MBTL1ABCB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150366888-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | Janssen Pharmaceuticals, Inc. | 2015-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150366888-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | PNP, NT5C3B, TYMP | LMNA 1903/4885PRKCA 1635/4885TSHR 2345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.