SCHEMBL1736155

SCHEMBL1736155

CCOc1ccc(-c2c3ccccc3c(-c3ccc(OCC)cc3)c3cc(Cl)ccc23)cc1.Clc1cccc2c(C#Cc3ccccc3)c3c(Cl)cccc3c(C#Cc3ccccc3)c12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.36
LMNA P02545 2/20 0.35
TP53 P04637 3/20 0.34
MAPT P10636 2/20 0.34
DYRK1A Q13627 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
ADK P55263 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PTPN22 Q9Y2R2 2/20 0.33
DPP4 P27487 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
PTPRC P08575 1/20 0.33
PTPN2 P17706 1/20 0.33
PTPN1 P18031 1/20 0.33
PTPRB P23467 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30459370 0.82 MAPT (0.44) EHMT2LMNATP53MAPTL3MBTL1
SCHEMBL428140 0.82 MAPT (0.44) EHMT2LMNATP53MAPTL3MBTL1
SCHEMBL3631512 0.80 L3MBTL1 (0.39) LMNATP53MAPTL3MBTL1KDM4E
SCHEMBL16267766 0.78 MAPT (0.46) EHMT2LMNATP53MAPTL3MBTL1
SCHEMBL15065239 0.77 GRM4 (0.36) DYRK1AL3MBTL1PTPN22PTGDR2PTPRC
SCHEMBL1353116 0.76 L3MBTL1 (0.44) LMNATP53MAPTL3MBTL1KDM4E
SCHEMBL427566 0.73 APP (0.46) LMNATP53MAPTDYRK1AL3MBTL1
SCHEMBL4143563 0.72 APP (0.34) DYRK1AL3MBTL1ADKPTPN22PTPRC
SCHEMBL432731 0.70 APP (0.43) TP53MAPTDYRK1AL3MBTL1KDM4E
SCHEMBL20454318 0.70 APP (0.43) TP53MAPTDYRK1AL3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2399971-A1 Chemiluminescent compositons and methods of making and using thereof Mega Glow, Inc (US) 2011-12-28 EP disclosed