Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | PDE6D | O43924 | 1/20 | 0.36 |
| ▸ | PDE6A | P16499 | 1/20 | 0.36 |
| ▸ | PDE6G | P18545 | 1/20 | 0.36 |
| ▸ | PDE6B | P35913 | 1/20 | 0.36 |
| ▸ | PDE6C | P51160 | 1/20 | 0.36 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20698175 | 0.85 | HSD11B1 (0.49) | HSD11B1P2RX7PTPN11PDE2APDE10A | |
| SCHEMBL29520229 | 0.82 | HSD11B1 (0.47) | HSD11B1P2RX7PTPN11PDE2APDE10A | |
| SCHEMBL171101 | 0.82 | HSD11B1 (0.47) | HSD11B1P2RX7PTPN11PDE2APDE10A | |
| SCHEMBL173619 | 0.82 | HSD11B1 (0.47) | HSD11B1P2RX7PTPN11PDE2APDE10A | |
| SCHEMBL28835084 | 0.82 | HSD11B1 (0.44) | HSD11B1P2RX7PTPN11PDE2APDE10A | |
| SCHEMBL28135840 | 0.80 | HSD11B1 (0.45) | HSD11B1P2RX7PTPN11PDE2APDE10A | |
| SCHEMBL17290428 | 0.79 | HSD11B1 (0.47) | HSD11B1P2RX7PDE10ASCN10ANISCH | |
| SCHEMBL1726063 | 0.78 | HSD11B1 (0.40) | HSD11B1P2RX7PTPN11PDE2APDE10A | |
| SCHEMBL171493 | 0.77 | MAPK1 (0.44) | HSD11B1P2RX7CYP3A4IGF1R | |
| SCHEMBL30308993 | 0.77 | MAPK1 (0.44) | HSD11B1P2RX7CYP3A4IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016026830-A1 | NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-02-25 | — | — | WO | disclosed |
| WO-2016026830-A1 | NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-02-25 | — | — | WO | disclosed |