Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.51 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | TACR2 | P21452 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.40 |
| ▸ | CDC25B | P30305 | 4/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336814 | 0.93 | POLB (0.49) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL12127987 | 0.93 | POLB (0.49) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL15973107 | 0.89 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL15973108 | 0.89 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL17363625 | 0.87 | TP53 (0.48) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL15972498 | 0.87 | TP53 (0.47) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL10351759 | 0.87 | TACR2 (0.49) | TACR2NT5EPTPN1CDC25BPTPN2 | |
| SCHEMBL10351760 | 0.87 | TACR2 (0.49) | TACR2NT5EPTPN1CDC25BPTPN2 | |
| SCHEMBL17368121 | 0.86 | L3MBTL1 (0.39) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL7582210 | 0.85 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2958905-B1 | CARBOHYDRATE PHOSPHONATE DERIVATIVES AS MODULATORS OF GLYCOSYLATION | AMGEN INC (US) | 2017-03-29 | — | — | EP | disclosed |
| US-9328134-B2 | Carbohydrate phosphonate derivatives as modulators of glycosylation | AMGEN INC. (US) | 2016-05-03 | — | — | US | disclosed |
| US-20150376221-A1 | Carbohydrate Phosphonate Derivatives as Modulators of Glycosylation | AMGEN INC. | 2015-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376221-A1 | Carbohydrate Phosphonate Derivatives as Modulators of Glycosylation | GALE, GPI, FUT6 | TP53 2322/4885MDM2 4478/4885MDM4 4516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.