SCHEMBL17364033

SCHEMBL17364033

CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)N[C@@H](Cc1ccccc1)C(=O)O)C(=O)N[C@@H](C=O)Cc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.69
▸ CTSK P43235 3/20 0.52
▸ CMA1 P23946 1/20 0.45
▸ CTRC Q99895 1/20 0.45
▸ NPY4R P50391 6/20 0.43
▸ NPY1R P25929 4/20 0.43
▸ CTSB P07858 1/20 0.43
▸ NPY2R P49146 3/20 0.43
▸ NPY5R Q15761 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26807763 1.00 SMN1; SMN2 (0.69) SMN1; SMN2CTSKCMA1CTRCNPY4R
Antipain SCHEMBL23132673 0.97 SMN1; SMN2 (0.74) SMN1; SMN2CTSKNPY4RNPY1RCTSB
Antipain SCHEMBL18328611 0.97 SMN1; SMN2 (0.74) SMN1; SMN2CTSKNPY4RNPY1RCTSB
Antipain SCHEMBL642095 0.97 SMN1; SMN2 (0.74) SMN1; SMN2CTSKNPY4RNPY1RCTSB
Antipain SCHEMBL5966873 0.97 SMN1; SMN2 (0.74) SMN1; SMN2CTSKNPY4RNPY1RCTSB
Antipain SCHEMBL14038024 0.97 SMN1; SMN2 (0.74) SMN1; SMN2CTSKNPY4RNPY1RCTSB
Antipain SCHEMBL3280675 0.97 SMN1; SMN2 (0.74) SMN1; SMN2CTSKNPY4RNPY1RCTSB
SCHEMBL17364037 0.96 SMN1; SMN2 (0.64) SMN1; SMN2CTSKNPY4RNPY1RNPY2R
SCHEMBL17364024 0.96 SMN1; SMN2 (0.64) SMN1; SMN2CTSKNPY4RNPY1RNPY2R
SCHEMBL20250612 0.91 SMN1; SMN2 (0.60) SMN1; SMN2CTSKNPY4RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590273-B2 Stabilized glycoside hydrolase variants NOVOZYMES A/S (DK) 2026-03-31 — — US disclosed
US-12391934-B2 Stabilized cellulase variants NOVOZYMES A/S (DK) 2025-08-19 — — US disclosed
EP-3953463-B1 STABILIZED GLYCOSIDE HYDROLASE VARIANTS NOVOZYMES AS (DK) 2025-08-06 — — EP disclosed
US-20250084394-A1 STABILIZED CELLULASE VARIANTS NOVOZYMES A/S (DK) 2025-03-13 — — US disclosed
US-12129498-B2 Stabilized endoglucanase variants NOVOZYMES A/S (DK) 2024-10-29 — — US disclosed
US-20230295591-A1 STABILIZED CELLULASE VARIANTS NOVOZYMES A/S (DK) 2023-09-21 — — US disclosed
US-20230287380-A1 STABILIZED CELLULASE VARIANTS NOVOZYMES A/S (DK) 2023-09-14 — — US disclosed
US-11661592-B2 Stabilized endoglucanase variants NOVOZYMES A/S (DK) 2023-05-30 — — US disclosed
US-20230143128-A1 CARBOHYDRATE BINDING MODULE VARIANTS NOVOZYMES A/S (DK) 2023-05-11 — — US disclosed
EP-4133066-A1 CARBOHYDRATE BINDING MODULE VARIANTS Novozymes A/S (DK) 2023-02-15 — — EP disclosed
CN-115210371-A Carbohydrate binding module variants 诺维信公司 2022-10-18 — — CN disclosed
US-20220186151-A1 STABILIZED GLYCOSIDE HYDROLASE VARIANTS NOVOZYMES A/S (DK) 2022-06-16 — — US disclosed
EP-3953463-A1 STABILIZED GLYCOSIDE HYDROLASE VARIANTS Novozymes A/S (DK) 2022-02-16 — — EP disclosed
CN-113795576-A Stabilized glycoside hydrolase variants 诺维信公司 2021-12-14 — — CN disclosed
US-20210363510-A1 STABILIZED CELLULASE VARIANTS NOVOZYMES A/S (DK) 2021-11-25 — — US disclosed
US-20210047628-A1 STABILIZED CELLULASE VARIANTS NOVOZYMES A/S (DK) 2021-02-18 — — US disclosed
CN-112272701-A Stabilized cellulase variants 诺维信公司 2021-01-26 — — CN disclosed
CN-112204137-A Stabilized cellulase variants 诺维信公司 2021-01-08 — — CN disclosed
US-20200140786-A1 USE OF ENZYME FOR WASHING, METHOD FOR WASHING AND WAREWASHING COMPOSITION NOVOZYMES A/S (DK) 2020-05-07 — — US disclosed
US-20150376554-A1 Industrial and Institutional Laundering Using Multi-Enzyme Compositions NOVOZYMES AS (DK) 2015-12-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230143128-A1 CARBOHYDRATE BINDING MODULE VARIANTS MGAM, MANBA, MAN2B1 SMN1; SMN2 3210/4885CTSK 1234/4885CMA1 75/4885
US-12590273-B2 Stabilized glycoside hydrolase variants IDUA, IDE, TREH SMN1; SMN2 2305/4885CTSK 1797/4885CMA1 414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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