Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14000685 | 1.00 | THRB (0.53) | THRBHTTCYP3A4ALDH1A1TSHR | |
| SCHEMBL13089478 | 0.96 | THRB (0.51) | THRBHTTCYP3A4ALDH1A1TSHR | |
| SCHEMBL1072168 | 0.96 | THRB (0.51) | THRBHTTCYP3A4ALDH1A1TSHR | |
| SCHEMBL17279039 | 0.96 | THRB (0.51) | THRBHTTCYP3A4ALDH1A1TSHR | |
| SCHEMBL22451142 | 0.96 | THRB (0.57) | THRBHTTCYP3A4ALDH1A1TSHR | |
| SCHEMBL12604124 | 0.95 | THRB (0.50) | THRBHTTCYP3A4ALDH1A1TSHR | |
| SCHEMBL14907448 | 0.95 | THRB (0.56) | THRBHTTCYP3A4ALDH1A1TSHR | |
| SCHEMBL25501133 | 0.95 | THRB (0.52) | THRBHTTCYP3A4ALDH1A1TSHR | |
| SCHEMBL18328876 | 0.94 | THRB (0.64) | THRBCYP3A4ALDH1A1TSHRNPC1 | |
| SCHEMBL15855554 | 0.94 | THRB (0.64) | THRBCYP3A4ALDH1A1TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9222022-B2 | Polymer-stabilized optical isotropic liquid crystal formulation and optical isotropic liquid crystal device | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2015-12-29 | — | — | US | disclosed |
| US-9222022-B2 | Polymer-stabilized optical isotropic liquid crystal formulation and optical isotropic liquid crystal device | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2015-12-29 | — | — | US | disclosed |