Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17364613 | 1.00 | SLC6A3 (0.30) | SLC6A3 | |
| SCHEMBL17365569 | 0.88 | EGFR (0.36) | SLC6A3 | |
| SCHEMBL17365510 | 0.88 | EGFR (0.36) | SLC6A3 | |
| SCHEMBL17364612 | 0.79 | HIF1A (0.33) | SLC6A3 | |
| SCHEMBL17364609 | 0.79 | HIF1A (0.33) | SLC6A3 | |
| SCHEMBL16113731 | 0.73 | UCHL1 (0.34) | — | |
| SCHEMBL17365509 | 0.71 | PDE4B (0.38) | SLC6A3 | |
| SCHEMBL17365468 | 0.71 | PDE4B (0.38) | SLC6A3 | |
| SCHEMBL12470552 | 0.70 | UCHL1 (0.34) | — | |
| SCHEMBL24658424 | 0.69 | HIF1A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221834-B2 | Cyclic amine substituted oxazolidinone CETP inhibitor | MERCK SHARP & DOHME CORP. (US) | 2015-12-29 | — | — | US | disclosed |