SCHEMBL17365337

SCHEMBL17365337

CCC[C@H](C)n1nnc2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 7/20 0.51
KEAP1 Q14145 1/20 0.46
CYP4Z1 Q86W10 6/20 0.45
HCAR3 P49019 1/20 0.43
POLB P06746 2/20 0.43
APAF1 O14727 1/20 0.43
MAPK1 P28482 1/20 0.42
ATM Q13315 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C9 P11712 1/20 0.42
THPO P40225 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15165686 1.00 SLC9A1 (0.51) SLC9A1KEAP1CYP4Z1HCAR3POLB
SCHEMBL24421779 1.00 SLC9A1 (0.51) SLC9A1KEAP1CYP4Z1HCAR3POLB
SCHEMBL22651915 0.89 SLC9A1 (0.55) SLC9A1KEAP1CYP4Z1HCAR3POLB
SCHEMBL27714321 0.88 SLC9A1 (0.56) SLC9A1KEAP1CYP4Z1HCAR3POLB
SCHEMBL11402863 0.86 HCAR3 (0.56) SLC9A1KEAP1CYP4Z1HCAR3POLB
SCHEMBL27136518 0.84 SLC9A1 (0.49) SLC9A1KEAP1CYP4Z1POLBAPAF1
SCHEMBL25613221 0.84 SLC9A1 (0.49) SLC9A1KEAP1CYP4Z1POLBAPAF1
SCHEMBL6427185 0.82 SLC9A1 (0.50) SLC9A1KEAP1CYP4Z1POLBAPAF1
SCHEMBL22032189 0.82 SLC9A1 (0.50) SLC9A1KEAP1CYP4Z1POLBAPAF1
SCHEMBL27635808 0.82 SLC9A1 (0.50) SLC9A1KEAP1CYP4Z1POLBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10375962-B2 Heterocycle derivatives as pesticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-08-13 US disclosed
US-20190021329-A1 HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-01-24 US disclosed
US-9221759-B2 Fluorophore chelated lanthanide luminescent probes with improved quantum efficiency RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2015-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10375962-B2 Heterocycle derivatives as pesticides DDT, ACHE, CBR1 SLC9A1 2799/4885KEAP1 254/4885CYP4Z1 274/4885
US-20190021329-A1 HETEROCYCLE DERIVATIVES AS PESTICIDES DDT, ACHE, CBR1 SLC9A1 2799/4885KEAP1 254/4885CYP4Z1 274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.