Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CLPP | Q16740 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14614747 | 0.81 | BCL2L1 (0.47) | SLC6A5L3MBTL1SIGMAR1ALDH1A1CYP2D6 | |
| SCHEMBL9829721 | 0.81 | MEN1 (0.54) | KMT2AMEN1CLPPTDP1ALDH1A1 | |
| SCHEMBL266771 | 0.80 | SLC6A5 (0.59) | SLC6A5SIGMAR1CLPP | |
| Hydrochloric Acid SCHEMBL31714128 | 0.78 | SLC6A5 (0.57) | SLC6A5SIGMAR1 | |
| SCHEMBL667489 | 0.78 | SIGMAR1 (0.62) | KMT2AMEN1GAASIGMAR1CLPP | |
| SCHEMBL2439744 | 0.78 | KDM4E (0.62) | KMT2AMEN1GAASIGMAR1SMN1; SMN2 | |
| Formaldehyde SCHEMBL27535190 | 0.77 | SLC6A5 (0.56) | SLC6A5SIGMAR1CLPP | |
| Benzylamine SCHEMBL27725263 | 0.76 | SLC6A5 (0.52) | SLC6A5KMT2AMEN1PRMT6SIGMAR1 | |
| SCHEMBL29067018 | 0.71 | SMN1; SMN2 (0.68) | KMT2AMEN1SIGMAR1CLPPSMN1; SMN2 | |
| SCHEMBL8109044 | 0.71 | SIGMAR1 (0.70) | KMT2AMEN1GAAATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757582-B1 | ARYLALKYLAMINES AND PROCESS FOR PRODUCTION THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2015-12-30 | — | — | EP | disclosed |