SCHEMBL14614747

SCHEMBL14614747

O=C1CCN(Cc2cccc(O)c2)C1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.47
DRD2 P14416 3/20 0.46
DRD3 P35462 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.44
SIGMAR1 Q99720 1/20 0.44
CHRM2 P08172 1/20 0.44
CHRM3 P20309 1/20 0.44
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
HBB P68871 1/20 0.43
HSD17B10 Q99714 1/20 0.43
SLC6A5 Q9Y345 1/20 0.42
COMT P21964 1/20 0.41
ENPP2 Q13822 1/20 0.41
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
HIF1A Q16665 1/20 0.40
DRD4 P21917 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16277146 0.90 DRD2 (0.51) BCL2L1DRD2DRD3SIGMAR1CHRM2
SCHEMBL9829721 0.81 MEN1 (0.54) ALDH1A1
SCHEMBL17366014 0.81 SLC6A5 (0.42) L3MBTL1SIGMAR1ALDH1A1SLC6A5CYP2D6
SCHEMBL266771 0.80 SLC6A5 (0.59) SIGMAR1SLC6A5
Hydrochloric Acid SCHEMBL31714128 0.78 SLC6A5 (0.57) SIGMAR1SLC6A5
SCHEMBL667489 0.78 SIGMAR1 (0.62) DRD3SIGMAR1CHRM2CHRM3ALDH1A1
SCHEMBL2439744 0.78 KDM4E (0.62) DRD2DRD3SIGMAR1CHRM3ALDH1A1
Formaldehyde SCHEMBL27535190 0.77 SLC6A5 (0.56) SIGMAR1SLC6A5
SCHEMBL27650580 0.76 PRMT6 (0.58) BCL2L1DRD2DRD3SIGMAR1ALDH1A1
SCHEMBL6310987 0.76 PRMT6 (0.62) BCL2L1DRD2DRD3ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1757582-A1 ARYLALKYLAMINES AND PROCESS FOR PRODUCTION THEREOF TANABE SEIYAKU CO., LTD. (JP) 2007-02-28 EP disclosed