Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14147814 | 0.90 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| SCHEMBL14138247 | 0.90 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| SCHEMBL838751 | 0.86 | GSK3B (0.41) | PDE4APDE4BPDE4CPDE4DGSK3A | |
| SCHEMBL35878 | 0.74 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| SCHEMBL13917311 | 0.73 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DGSK3A | |
| SCHEMBL20738815 | 0.73 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DGSK3A | |
| SCHEMBL21301512 | 0.73 | PLA2G4A (0.35) | PDE4APDE4BPDE4CPDE4DGSK3A | |
| SCHEMBL5178897 | 0.73 | CYP3A4 (0.57) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2730449 | 0.71 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| Formaldehyde SCHEMBL8709282 | 0.70 | CYP3A4 (0.38) | PDE4APDE4BPDE4CPDE4DHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2960333-A1 | COMPOSITION FOR INHIBITING GENE EXPRESSION AND USES THEREOF | Idera Pharmaceuticals, Inc. (US) | 2015-12-30 | — | — | EP | disclosed |