Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.71 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.70 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.70 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.60 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1315526 | 0.89 | PTPN1 (0.87) | PTPN1CACNA1BAPBA1HDAC2HDAC8 | |
| SCHEMBL1128154 | 0.88 | KMT2A (0.78) | PTPN1CACNA1BAPBA1HDAC2HDAC8 | |
| SCHEMBL14715847 | 0.87 | PTPN1 (0.84) | PTPN1CACNA1BAPBA1HDAC2HDAC8 | |
| SCHEMBL26953087 | 0.85 | PTPN1 (0.88) | PTPN1CACNA1BAPBA1HDAC2HDAC8 | |
| SCHEMBL24202631 | 0.85 | SIRT1 (0.83) | PTPN1CACNA1BAPBA1HDAC2HDAC8 | |
| N-Phenylbenzamide SCHEMBL5402750 | 0.85 | SIRT1 (0.83) | PTPN1CACNA1BAPBA1HDAC2HDAC8 | |
| N-Phenylbenzamide SCHEMBL31966 | 0.85 | SIRT1 (0.83) | PTPN1CACNA1BAPBA1HDAC2HDAC8 | |
| SCHEMBL178425 | 0.84 | RAB9A (0.85) | PTPN1CACNA1BAPBA1HDAC2HDAC8 | |
| SCHEMBL3659389 | 0.83 | FFAR1 (0.79) | PTPN1CACNA1BAPBA1HDAC2HDAC8 | |
| SCHEMBL30549187 | 0.83 | PTPN1 (1.00) | PTPN1HDAC2HDAC8HDAC6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290592-B2 | Poly(diphenylacetylene) compound, preparation method therefor, and use thereof as optical isomer separating agent | NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY (JP) | 2016-03-22 | — | — | US | disclosed |
| US-20150376309-A1 | NEW POLY(DIPHENYLACETYLENE) COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF AS OPTICAL ISOMER SEPARATING AGENT | National University Corporation Kanazawa University of Ishikawa ,Japan | 2015-12-31 | — | — | US | disclosed |