Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777464 | 0.70 | ADORA1 (0.41) | ADORA1CDK5CDK5R1NOS1ADORA2A | |
| SCHEMBL30590049 | 0.70 | ADORA1 (0.41) | ADORA1CDK5CDK5R1NOS1ADORA2A | |
| SCHEMBL21050252 | 0.70 | PRKD3 (0.42) | ADORA1CDK5CDK5R1NOS1ADORA2A | |
| SCHEMBL29665061 | 0.69 | ADORA1 (0.40) | ADORA1CDK5CDK5R1NOS1ADORA2A | |
| SCHEMBL5483576 | 0.69 | ADORA1 (0.40) | ADORA1CDK5CDK5R1NOS1ADORA2A | |
| Hydrochloric Acid SCHEMBL17364322 | 0.67 | CA12 (0.35) | — | |
| Hydrochloric Acid SCHEMBL17364318 | 0.67 | NPC1 (0.31) | — | |
| SCHEMBL29661338 | 0.65 | ADORA1 (0.43) | ADORA1NOS1ADORA2A | |
| SCHEMBL29552357 | 0.65 | ADORA1 (0.41) | ADORA1CDK5CDK5R1NOS1ADORA2A | |
| SCHEMBL20394079 | 0.65 | ADORA1 (0.41) | ADORA1CDK5CDK5R1NOS1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150376219-A1 | Selective Preparations of Purine Nucleosides and Nucleotides: Reagents and Methods | ZHONG MINGHONG (US) | 2015-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376219-A1 | Selective Preparations of Purine Nucleosides and Nucleotides: Reagents and Methods | PNP, ATIC, NT5C3B | ADORA1 174/4885CDK5 1348/4885CDK5R1 2882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.