Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17367475 | 0.89 | PTK2 (0.40) | PTGS1LMNAL3MBTL1CYP2C9CYP2D6 | |
| SCHEMBL17367478 | 0.82 | ALDH1A1 (0.42) | PTGS1LMNACYP2C9CYP2D6CYP3A4 | |
| SCHEMBL17367479 | 0.78 | MAPT (0.36) | L3MBTL1CYP2C9CYP2D6HSD11B1CYP3A4 | |
| SCHEMBL17367481 | 0.78 | PTGS1 (0.30) | PTGS1CYP2C9CYP2D6CYP3A4HPGD | |
| SCHEMBL17367484 | 0.78 | APP (0.35) | CYP2C9CYP2D6CYP3A4APPCYP2C19 | |
| SCHEMBL30238017 | 0.73 | PTK2 (0.42) | PTGS1LMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL1147544 | 0.72 | MAPT (0.50) | PTGS1LMNAALDH1A1MAPTHPGD | |
| SCHEMBL17367489 | 0.71 | PRKAB2 (0.40) | CYP2C9CYP2D6HSD11B1CYP3A4APP | |
| SCHEMBL17367490 | 0.71 | APP (0.37) | CYP2C9CYP2D6CYP3A4APPCYP2C19 | |
| SCHEMBL17367487 | 0.71 | PRKAB2 (0.35) | CYP2C9CYP2D6APPCYP2C19AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150376160-A1 | HALOGEN-SUBSTITUTED HETEROCYCLIC COMPOUND | UBE INDUSTRIES, LTD. (JP) | 2015-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376160-A1 | HALOGEN-SUBSTITUTED HETEROCYCLIC COMPOUND | LPAR3, LPAR1, LPAR2 | PTGS1 2492/4885LMNA 2850/4885L3MBTL1 2826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.