Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.30 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17367487 | 0.91 | PRKAB2 (0.35) | CYP2C9CYP2C19APPCYP2D6 | |
| SCHEMBL17367479 | 0.84 | MAPT (0.36) | CYP2C9CYP2C19APPCYP2D6KDM4E | |
| SCHEMBL17367484 | 0.84 | APP (0.35) | CYP2C9CYP2C19APPCYP2D6CYP3A4 | |
| SCHEMBL17367474 | 0.78 | PTGS1 (0.38) | PTGS1PTGS2CYP2C9CYP2C19APP | |
| SCHEMBL17367489 | 0.75 | PRKAB2 (0.40) | CYP2C9CYP2C19APPCYP2D6CYP3A4 | |
| SCHEMBL17367490 | 0.75 | APP (0.37) | CYP2C9CYP2C19APPCYP2D6CYP3A4 | |
| SCHEMBL15854181 | 0.75 | OPRM1 (0.44) | KDM4E | |
| SCHEMBL17367480 | 0.74 | PRKAB2 (0.32) | CYP2C9CYP2C19APPCYP3A4 | |
| SCHEMBL15854163 | 0.72 | APP (0.41) | CYP2C9CYP2C19APPCYP2D6CYP3A4 | |
| SCHEMBL17226296 | 0.72 | APP (0.41) | CYP2C9CYP2C19APPCYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150376160-A1 | HALOGEN-SUBSTITUTED HETEROCYCLIC COMPOUND | UBE INDUSTRIES, LTD. (JP) | 2015-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376160-A1 | HALOGEN-SUBSTITUTED HETEROCYCLIC COMPOUND | LPAR3, LPAR1, LPAR2 | PTGS1 2492/4885PTGS2 3564/4885CYP2C9 2611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.