Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CCR1 | P32246 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17367679 | 0.91 | TSHR (0.55) | TSHRALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL17367681 | 0.91 | TSHR (0.55) | TSHRALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL15918290 | 0.83 | CCR1 (0.51) | TSHRALDH1A1CCR1KDM4EEPHX2 | |
| SCHEMBL15915551 | 0.83 | CCR1 (0.51) | TSHRALDH1A1CCR1KDM4EEPHX2 | |
| SCHEMBL15916089 | 0.83 | CCR1 (0.56) | TSHRALDH1A1POLBHTTAKR1C3 | |
| SCHEMBL17367675 | 0.82 | LMNA (0.65) | TSHRALDH1A1LMNAPOLBHTT | |
| Hydrochloric Acid SCHEMBL15916404 | 0.82 | CCR1 (0.50) | TSHRALDH1A1CCR1KDM4EEPHX2 | |
| SCHEMBL29973515 | 0.80 | TSHR (0.66) | TSHRALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL15917236 | 0.80 | TSHR (0.71) | TSHRALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL15915552 | 0.80 | ALOX5AP (0.48) | TSHRALDH1A1HTTCCR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745328-B2 | Flap modulators | JANSSEN PHARMACEUTICA NV (BE) | 2017-08-29 | — | — | US | disclosed |
| US-20150376212-A1 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376212-A1 | FLAP MODULATORS | FEN1, PGF, TBXA2R | TSHR 2884/4885ALDH1A1 200/4885LMNA 3880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.