Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | CASP1 | P29466 | 6/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 5/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | MET | P08581 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1738913 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CASP1CYP1A2CYP3A4HSD17B10 | |
| Hydrochloric Acid SCHEMBL1736686 | 0.99 | ALDH1A1 (0.46) | ALDH1A1CASP1CYP1A2CYP3A4HSD17B10 | |
| Hydrochloric Acid SCHEMBL1738020 | 0.99 | ALDH1A1 (0.46) | ALDH1A1CASP1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL1739797 | 0.94 | ALDH1A1 (0.46) | ALDH1A1CASP1CYP1A2CYP3A4HSD17B10 | |
| Hydrochloric Acid SCHEMBL1735548 | 0.93 | ALDH1A1 (0.44) | ALDH1A1CASP1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL1738892 | 0.92 | MCL1 (0.48) | ALDH1A1CASP1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL1737422 | 0.91 | LMNA (0.46) | ALDH1A1MAPTTP53KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL1735775 | 0.91 | MCL1 (0.47) | ALDH1A1CASP1CYP1A2CYP3A4HSD17B10 | |
| Hydrochloric Acid SCHEMBL1736621 | 0.90 | LMNA (0.46) | ALDH1A1MAPTTP53KMT2AMEN1 | |
| SCHEMBL1737684 | 0.90 | TP53 (0.47) | ALDH1A1CYP1A2CYP3A4MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |