Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.74 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30451705 | 1.00 | AKR1B1 (0.74) | AKR1B1HSPA5TSHRHIF1ACYP2D6 | |
| SCHEMBL4031727 | 0.89 | AKR1B1 (0.67) | AKR1B1HSPA5TSHRMPOLMNA | |
| SCHEMBL4006576 | 0.89 | AKR1B1 (0.65) | AKR1B1HSPA5TSHRHIF1ACYP2D6 | |
| SCHEMBL30610413 | 0.87 | AKR1B1 (0.63) | AKR1B1HSPA5TSHRHIF1ACYP2D6 | |
| SCHEMBL8100591 | 0.87 | AKR1B1 (0.69) | AKR1B1HSPA5TSHRHIF1ACYP2D6 | |
| SCHEMBL156141 | 0.87 | AKR1B1 (0.63) | AKR1B1HSPA5TSHRHIF1ACYP2D6 | |
| SCHEMBL28125524 | 0.87 | AKR1B1 (0.63) | AKR1B1HSPA5TSHRHIF1ACYP2D6 | |
| SCHEMBL72309 | 0.85 | AKR1B1 (1.00) | AKR1B1HSPA5TSHRHIF1ACYP2D6 | |
| SCHEMBL30449014 | 0.85 | AKR1B1 (1.00) | AKR1B1HSPA5TSHRHIF1ACYP2D6 | |
| SCHEMBL2240152 | 0.83 | AKR1B1 (0.59) | AKR1B1HSPA5TSHRHIF1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116265440-B | Salicylic ketone spliced pyridone compound and preparation method and application thereof | 贵州大学 | 2024-09-27 | — | — | CN | disclosed |
| CN-116265440-B | Salicylic ketone spliced pyridone compound and preparation method and application thereof | 贵州大学 | 2024-09-27 | — | — | CN | disclosed |
| CN-117534692-A | Boron-containing multifunctional targeted drug conjugates, their use and methods of their preparation | 好利安科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-110612303-B | Boron-containing multifunctional targeted drug conjugates, their use and methods of their preparation | 好利安科技有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-116265440-A | Salicylic ketone spliced pyridone compound and preparation method and application thereof | 贵州大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-116265440-A | Salicylic ketone spliced pyridone compound and preparation method and application thereof | 贵州大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-111518063-A | Method for preparing benzofuran from furan by one-step method | 中国科学技术大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-106102690-A | Dental composition | 登特斯普伊德特雷有限公司 | 2016-11-09 | — | — | CN | disclosed |
| EP-2393610-B1 | COATING AGENT FOR CORROSION-RESISTANT COATINGS | BASF COATINGS GMBH (DE) | 2014-04-30 | — | — | EP | disclosed |
| EP-2393610-A1 | COATING AGENT FOR CORROSION-RESISTANT COATINGS | BASF Coatings GmbH (DE) | 2011-12-14 | — | — | EP | disclosed |
| US-7473786-B1 | Methods and systems for preparing fused heterocyclic compounds using copper(I) catalysts | UNIVERSITY OF MASSACHUSETTS (US) | 2009-01-06 | — | — | US | disclosed |
| US-5512059-A | DYEING POLYUREHTANE ELASTIC FIBERS INCLUDING CHLORINE-INDUCED DEGRADATION INHIBITORS THAT DO NO ELUTE OUT | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1996-04-30 | — | — | US | disclosed |
| US-5456960-A | A multicomponent yarn comprising a polyurethane elastic fiber containing one or more chlorination resistant inhibitors selected from the group consisting of oxides and hydroxides of magnesium, zinc, aluminum and hydrotalcite | TOYO BOSEKI KABUSHIHI KAISHA (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0489395-B1 | Dyed mixed knit fabric and method for its manufacture | TOYO BOSEKI (JP) | 1995-09-27 | — | — | EP | disclosed |
| EP-0489395-A1 | Dyed mixed knit fabric and method for its manufacture | Toyo Boseki Kabushiki Kaisha (JP) | 1992-06-10 | — | — | EP | disclosed |
| US-4594353-A | Azolyl-furan-derivatives having fungicide activity | MONTEDISON S.P.A. (IT) | 1986-06-10 | — | — | US | disclosed |
| EP-0042617-B1 | PROCESS FOR THE PRODUCTION OF SHAPED ARTICLES AND COATINGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-04-03 | — | — | EP | disclosed |
| EP-0123931-A2 | Furan derivatives having fungicide activity | Montedison S.p.A. (IT) | 1984-11-07 | — | — | EP | disclosed |
| US-4399268-A | POLYEPOXIDE, SUBSTITUTED AMINOPHENOL | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-08-16 | — | — | US | disclosed |
| EP-0042617-A1 | Process for the production of shaped articles and coatings | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-12-30 | — | — | EP | disclosed |