Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.65 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30451705 | 0.89 | AKR1B1 (0.74) | AKR1B1HSPA5TSHRCYP2D6HIF1A | |
| SCHEMBL1737314 | 0.89 | AKR1B1 (0.74) | AKR1B1HSPA5TSHRCYP2D6HIF1A | |
| SCHEMBL30610413 | 0.81 | AKR1B1 (0.63) | AKR1B1HSPA5TSHRCYP2D6HIF1A | |
| SCHEMBL156141 | 0.81 | AKR1B1 (0.63) | AKR1B1HSPA5TSHRCYP2D6HIF1A | |
| SCHEMBL28125524 | 0.81 | AKR1B1 (0.63) | AKR1B1HSPA5TSHRCYP2D6HIF1A | |
| SCHEMBL8100591 | 0.81 | AKR1B1 (0.69) | AKR1B1HSPA5TSHRCYP2D6HIF1A | |
| SCHEMBL72309 | 0.79 | AKR1B1 (1.00) | AKR1B1HSPA5TSHRCYP2D6HIF1A | |
| SCHEMBL30449014 | 0.79 | AKR1B1 (1.00) | AKR1B1HSPA5TSHRCYP2D6HIF1A | |
| SCHEMBL4031727 | 0.79 | AKR1B1 (0.67) | AKR1B1HSPA5TSHRMPO | |
| SCHEMBL29233348 | 0.79 | IAPP (0.59) | AKR1B1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735266-B1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE 1-ERYTHRO-2-AMINO-1-PHENYL-1-PROPANOL | EMMELLEN BIOTECH PHARMACEUTICA (IN) | 2009-06-24 | — | — | EP | disclosed |