Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.74 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1737314 | 1.00 | AKR1B1 (0.74) | AKR1B1HSPA5TSHRHIF1ACYP2D6 | |
| SCHEMBL4031727 | 0.89 | AKR1B1 (0.67) | AKR1B1HSPA5TSHRMPOLMNA | |
| SCHEMBL4006576 | 0.89 | AKR1B1 (0.65) | AKR1B1HSPA5TSHRHIF1ACYP2D6 | |
| SCHEMBL8100591 | 0.87 | AKR1B1 (0.69) | AKR1B1HSPA5TSHRHIF1ACYP2D6 | |
| SCHEMBL30610413 | 0.87 | AKR1B1 (0.63) | AKR1B1HSPA5TSHRHIF1ACYP2D6 | |
| SCHEMBL156141 | 0.87 | AKR1B1 (0.63) | AKR1B1HSPA5TSHRHIF1ACYP2D6 | |
| SCHEMBL28125524 | 0.87 | AKR1B1 (0.63) | AKR1B1HSPA5TSHRHIF1ACYP2D6 | |
| SCHEMBL30449014 | 0.85 | AKR1B1 (1.00) | AKR1B1HSPA5TSHRHIF1ACYP2D6 | |
| SCHEMBL72309 | 0.85 | AKR1B1 (1.00) | AKR1B1HSPA5TSHRHIF1ACYP2D6 | |
| SCHEMBL2240152 | 0.83 | AKR1B1 (0.59) | AKR1B1HSPA5TSHRHIF1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116265440-B | Salicylic ketone spliced pyridone compound and preparation method and application thereof | 贵州大学 | 2024-09-27 | — | — | CN | claimed |
| CN-116265440-A | Salicylic ketone spliced pyridone compound and preparation method and application thereof | 贵州大学 | 2023-06-20 | — | — | CN | claimed |
| CN-116265440-B | Salicylic ketone spliced pyridone compound and preparation method and application thereof | 贵州大学 | 2024-09-27 | — | — | CN | disclosed |
| US-20240150379-A1 | Boronated Multifunctional Targeting Drug Conjugates, Their Uses and Methods for Their Preparation | HOVIONE SCIENTIA LIMITED (IE) | 2024-05-09 | — | — | US | disclosed |
| CN-117534692-A | Boron-containing multifunctional targeted drug conjugates, their use and methods of their preparation | 好利安科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| US-11884687-B2 | Boronated multifunctional targeting drug conjugates, their uses and methods for their preparation | HOVIONE SCIENTIA LIMITED (IE) | 2024-01-30 | — | — | US | disclosed |
| CN-110612303-B | Boron-containing multifunctional targeted drug conjugates, their use and methods of their preparation | 好利安科技有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-116265440-A | Salicylic ketone spliced pyridone compound and preparation method and application thereof | 贵州大学 | 2023-06-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11884687-B2 | Boronated multifunctional targeting drug conjugates, their uses and methods for their preparation | FOLR2, FOLR1, ABCG2 | AKR1B1 722/4885HSPA5 813/4885TSHR 433/4885 |
| US-20240150379-A1 | Boronated Multifunctional Targeting Drug Conjugates, Their Uses and Methods for Their Preparation | FOLR2, FOLR1, ABCG2 | AKR1B1 722/4885HSPA5 813/4885TSHR 433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.