SCHEMBL1737338

SCHEMBL1737338

CSc1ccc(-c2nccc3c(C)c(C)n(Cc4ccccc4)c23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 1/20 0.44
MCL1 Q07820 3/20 0.42
POLB P06746 3/20 0.38
TSHR P16473 3/20 0.38
KDM4E B2RXH2 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
NR2F2 P24468 1/20 0.38
MAPK1 P28482 2/20 0.37
HTT P42858 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ALDH1A1 P00352 1/20 0.37
DYRK1A Q13627 1/20 0.36
THRB P10828 1/20 0.36
PTGS1 P23219 2/20 0.35
PTGS2 P35354 2/20 0.35
LMNA P02545 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1736565 0.99 FABP4 (0.44) FABP4MCL1POLBTSHRKDM4E
SCHEMBL1737492 0.91 RAB9A (0.44) FABP4MCL1TSHRKDM4EMEN1
Hydrochloric Acid SCHEMBL1736491 0.90 RAB9A (0.44) FABP4MCL1TSHRKDM4EMEN1
SCHEMBL1739417 0.90 MAPT (0.39) FABP4MCL1POLBTSHRKDM4E
SCHEMBL1738133 0.89 CYP11B1 (0.38) FABP4MCL1POLBKDM4ENPSR1
SCHEMBL1737107 0.89 FABP4 (0.51) FABP4MCL1POLBTSHRKDM4E
Hydrochloric Acid SCHEMBL1737358 0.89 NR1I3 (0.39) FABP4MCL1POLBTSHRKDM4E
SCHEMBL1738879 0.89 MCL1 (0.43) MCL1TSHRMEN1KMT2ANPC1
Hydrochloric Acid SCHEMBL1736481 0.88 CYP11B1 (0.37) FABP4MCL1POLBKDM4ENPSR1
SCHEMBL1737158 0.88 MCL1 (0.50) FABP4MCL1POLBTSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1784404-B1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2011-11-16 EP claimed
US-20110263306-A1 COMPUTER SYSTEM AND PROGRAM NAMCO BANDAI GAMES INC. (JP) 2011-10-27 US claimed
EP-1784404-A4 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2009-09-09 EP disclosed
EP-1784404-A1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF Yuhan Corporation (KR) 2007-05-16 EP disclosed
WO-2006025716-A1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO disclosed