Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 6/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.42 |
| ▸ | GCGR | P47871 | 4/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | MATK | P42679 | 1/20 | 0.36 |
| ▸ | FRK | P42685 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1735513 | 0.99 | MCL1 (0.42) | MCL1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL1738892 | 0.92 | MCL1 (0.48) | MCL1MAPK1LMNARAB9ACLK1 | |
| SCHEMBL1737492 | 0.91 | RAB9A (0.44) | MCL1MAPK14MAPK13MAPK12MAPK11 | |
| Hydrochloric Acid SCHEMBL1735775 | 0.91 | MCL1 (0.47) | MCL1MAPK1LMNARAB9ACLK1 | |
| SCHEMBL1739417 | 0.90 | MAPT (0.39) | MCL1MAPK1NPC1LMNATSHR | |
| Hydrochloric Acid SCHEMBL1736491 | 0.90 | RAB9A (0.44) | MCL1MAPK14MAPK13MAPK12MAPK11 | |
| Hydrochloric Acid SCHEMBL1737358 | 0.89 | NR1I3 (0.39) | MCL1MAPK1NPC1LMNATSHR | |
| SCHEMBL1737338 | 0.89 | FABP4 (0.44) | MCL1MAPK1NPC1LMNATSHR | |
| SCHEMBL1739805 | 0.89 | MCL1 (0.46) | MCL1MAPK1LMNARAB9ACLK1 | |
| SCHEMBL1737438 | 0.89 | MCL1 (0.46) | MCL1MAPK1LMNARAB9ACLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |