Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1738394 | 0.99 | NPC1 (0.37) | NPC1RAB9ATSHRSMN1; SMN2LMNA | |
| SCHEMBL1737420 | 0.89 | KDM4E (0.37) | NPC1RAB9ATSHRSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL1736963 | 0.88 | KDM4E (0.37) | NPC1RAB9ATSHRSMN1; SMN2LMNA | |
| SCHEMBL1737488 | 0.86 | KDM4E (0.39) | NPC1RAB9ATSHRSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL1738061 | 0.85 | KDM4E (0.38) | NPC1RAB9ATSHRSMN1; SMN2MAPK1 | |
| SCHEMBL1737165 | 0.84 | FABP4 (0.44) | NPC1RAB9ATSHRSMN1; SMN2LMNA | |
| SCHEMBL1739165 | 0.84 | KDM4E (0.40) | NPC1RAB9ATSHRSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL1737555 | 0.83 | FABP4 (0.43) | NPC1RAB9ATSHRSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL1737747 | 0.83 | KDM4E (0.39) | NPC1RAB9ATSHRSMN1; SMN2LMNA | |
| SCHEMBL1737569 | 0.83 | PKM (0.39) | NPC1RAB9ASMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |