Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 12/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL695033 | 0.78 | BRPF1 (0.51) | BRPF1CA1CA2ALDH1A1LMNA | |
| SCHEMBL14493605 | 0.78 | BRPF1 (0.51) | BRPF1METKCNH2NPC1RAB9A | |
| SCHEMBL1201332 | 0.78 | IGFBP3 (0.47) | BRPF1METKCNH2NPC1RAB9A | |
| SCHEMBL11081744 | 0.76 | EDNRA (0.49) | NPC1RAB9ACA1CA2ALDH1A1 | |
| SCHEMBL8996768 | 0.76 | MET (0.47) | BRPF1METKCNH2MAPK10CA1 | |
| SCHEMBL1202612 | 0.76 | LCK (0.49) | BRPF1METJAK2ABL1ALDH1A1 | |
| SCHEMBL22613423 | 0.75 | SLC22A12 (0.46) | METNPC1RAB9AJAK2ALDH1A1 | |
| SCHEMBL30186176 | 0.74 | CA1 (0.67) | BRPF1CA1CA2ALDH1A1LMNA | |
| SCHEMBL171701 | 0.74 | CA1 (0.67) | BRPF1CA1CA2ALDH1A1LMNA | |
| SCHEMBL29625693 | 0.74 | CA1 (0.67) | BRPF1CA1CA2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015197028-A1 | COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-12-30 | — | — | WO | disclosed |