Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1736899 | 0.99 | MAPT (0.48) | MAPTCES2GRIN1GRIN2BACHE | |
| SCHEMBL1738897 | 0.91 | USP2 (0.48) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL1735606 | 0.91 | MAPT (0.43) | MAPTGRIN1GRIN2BLMNAKDM4E | |
| SCHEMBL1738227 | 0.90 | CYP3A4 (0.50) | MAPTGRIN1GRIN2BLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL1738700 | 0.90 | USP2 (0.47) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL1738536 | 0.89 | GRIN1 (0.41) | MAPTGRIN1GRIN2BLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL1738352 | 0.89 | MAPT (0.43) | MAPTGRIN1GRIN2BLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL1736823 | 0.89 | CYP3A4 (0.49) | MAPTGRIN1GRIN2BLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL1736852 | 0.89 | GRIN1 (0.40) | MAPTGRIN1GRIN2BLMNAKDM4E | |
| SCHEMBL1738241 | 0.88 | FABP4 (0.44) | MAPTGRIN1GRIN2BKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |