SCHEMBL1735606

SCHEMBL1735606

Cc1c(C)n(Cc2cccc(F)c2)c2c(-c3ccc(F)cc3)nccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.43
HTR6 P50406 1/20 0.43
MCL1 Q07820 1/20 0.41
KDM4E B2RXH2 4/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
NTSR1 P30989 1/20 0.41
HTT P42858 1/20 0.41
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C19 P33261 2/20 0.40
ATM Q13315 1/20 0.40
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
GRIN1 Q05586 3/20 0.39
GRIN2B Q13224 3/20 0.39
FABP4 P15090 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1738352 0.99 MAPT (0.43) MAPTHTR6MCL1KDM4EMEN1
SCHEMBL1738536 0.94 GRIN1 (0.41) MAPTHTR6MCL1KDM4EMEN1
Hydrochloric Acid SCHEMBL1736852 0.93 GRIN1 (0.40) MAPTHTR6MCL1KDM4EMEN1
SCHEMBL1738241 0.93 FABP4 (0.44) MAPTMCL1KDM4EMEN1KMT2A
SCHEMBL1738189 0.92 ALDH1A1 (0.40) MAPTHTR6MCL1KDM4EMEN1
SCHEMBL1739046 0.92 MAPT (0.43) MAPTHTR6MCL1KDM4EMEN1
Hydrochloric Acid SCHEMBL1736922 0.92 FABP4 (0.43) MAPTMCL1KDM4EMEN1KMT2A
Hydrochloric Acid SCHEMBL1737359 0.91 ALDH1A1 (0.39) MAPTHTR6MCL1KDM4EMEN1
Hydrochloric Acid SCHEMBL1737093 0.91 MAPT (0.43) MAPTHTR6MCL1KDM4EMEN1
SCHEMBL1739105 0.91 HTT (0.40) MAPTHTR6MCL1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1784404-B1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2011-11-16 EP claimed
US-20110263306-A1 COMPUTER SYSTEM AND PROGRAM NAMCO BANDAI GAMES INC. (JP) 2011-10-27 US claimed
EP-1784404-B1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2011-11-16 EP disclosed
US-20110263306-A1 COMPUTER SYSTEM AND PROGRAM NAMCO BANDAI GAMES INC. (JP) 2011-10-27 US disclosed