Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1736852 | 0.99 | GRIN1 (0.40) | GRIN1GRIN2BMCL1KDM4ECYP1A2 | |
| SCHEMBL1735606 | 0.94 | MAPT (0.43) | GRIN1GRIN2BMCL1KDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL1738352 | 0.93 | MAPT (0.43) | GRIN1GRIN2BMCL1KDM4ECYP1A2 | |
| SCHEMBL1738241 | 0.92 | FABP4 (0.44) | GRIN1GRIN2BMCL1KDM4ECYP1A2 | |
| SCHEMBL1738189 | 0.91 | ALDH1A1 (0.40) | GRIN1GRIN2BMCL1KDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL1736922 | 0.91 | FABP4 (0.43) | GRIN1GRIN2BMCL1KDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL1737359 | 0.90 | ALDH1A1 (0.39) | GRIN1GRIN2BMCL1KDM4ECYP1A2 | |
| SCHEMBL1738578 | 0.90 | MCL1 (0.42) | MCL1CYP1A2CYP3A4CYP2C19ATM | |
| SCHEMBL1739105 | 0.89 | HTT (0.40) | GRIN1GRIN2BMCL1KDM4ECYP1A2 | |
| SCHEMBL1737517 | 0.89 | MAPT (0.49) | GRIN1GRIN2BKDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |