Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 17/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13503309 | 0.74 | CYP1A2 (0.43) | PSMB5 | |
| SCHEMBL15824972 | 0.72 | EGFR (0.71) | PSMB5EGFR | |
| SCHEMBL17376088 | 0.69 | NTSR1 (0.54) | NTSR1 | |
| SCHEMBL17376207 | 0.69 | NTSR1 (0.54) | NTSR1 | |
| SCHEMBL3559456 | 0.68 | HRH3 (0.43) | — | |
| SCHEMBL1118514 | 0.67 | HRH3 (0.39) | NTSR1 | |
| SCHEMBL3570338 | 0.67 | TDP1 (0.41) | — | |
| SCHEMBL30200310 | 0.67 | HTR3A (0.41) | EGFR | |
| SCHEMBL15819435 | 0.67 | HTR3A (0.41) | EGFR | |
| SCHEMBL17376288 | 0.66 | NTSR1 (0.57) | NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160961-A2 | SMALL MOLECULE AGONISTS OF NEUROTENSIN RECEPTOR 1 | Sanford-Burnham Medical Research Institute (US) | 2017-05-03 | — | — | EP | disclosed |
| WO-2015200534-A2 | SMALL MOLECULE AGONISTS OF NEUROTENSIN RECEPTOR 1 | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2015-12-30 | — | — | WO | disclosed |