Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17378 | 1.00 | POLB (0.40) | POLBMAPK1MAPTNUDT1L3MBTL1 | |
| SCHEMBL8568879 | 0.82 | NUDT1 (0.39) | POLBMAPK1MAPTNUDT1L3MBTL1 | |
| SCHEMBL17609 | 0.76 | ADRB1 (0.36) | NPSR1GAARAB9AKMT2ANPC1 | |
| SCHEMBL17608 | 0.76 | ADRB1 (0.36) | NPSR1GAARAB9AKMT2ANPC1 | |
| SCHEMBL8153396 | 0.76 | L3MBTL1 (0.44) | POLBMAPK1MAPTNUDT1L3MBTL1 | |
| SCHEMBL17379 | 0.73 | L3MBTL1 (0.36) | NUDT1L3MBTL1PIM1PIM2SMN1; SMN2 | |
| SCHEMBL29154 | 0.73 | NUDT1 (0.69) | MAPTNUDT1L3MBTL1PIM1PIM2 | |
| SCHEMBL29625490 | 0.73 | NUDT1 (0.69) | MAPTNUDT1L3MBTL1PIM1PIM2 | |
| SCHEMBL17658 | 0.71 | — | — | |
| SCHEMBL17657 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025460-A1 | OXADIAZOLINONE DERIVATIVES AND USE THEREOF IN PEST CONTROL | BAYER CROPSCIENCE AG (DE) | 2012-03-01 | — | — | WO | disclosed |