Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 5/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.38 |
| ▸ | RELA | Q04206 | 4/20 | 0.38 |
| ▸ | MASP2 | O00187 | 3/20 | 0.37 |
| ▸ | F2 | P00734 | 8/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PROC | P04070 | 1/20 | 0.37 |
| ▸ | TMPRSS6 | Q8IU80 | 6/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18875515 | 0.87 | F2 (0.45) | PSMB5NFKB1NFKB2RELAMASP2 | |
| SCHEMBL17381407 | 0.79 | F2 (0.44) | PSMB5NFKB1NFKB2RELAMASP2 | |
| SCHEMBL17381408 | 0.78 | F2 (0.53) | MASP2F2KLKB1F10PLG | |
| SCHEMBL17366097 | 0.75 | F2 (0.49) | PSMB5NFKB1NFKB2RELAMASP2 | |
| SCHEMBL18875317 | 0.75 | F2 (0.49) | PSMB5NFKB1NFKB2RELAMASP2 | |
| SCHEMBL18878673 | 0.74 | F10 (0.50) | PSMB5NFKB1NFKB2RELAMASP2 | |
| SCHEMBL20117570 | 0.72 | MASP2 (0.45) | PSMB5NFKB1NFKB2RELAMASP2 | |
| SCHEMBL8354790 | 0.71 | F2 (0.49) | F2KLKB1F10PLGPROC | |
| SCHEMBL8358318 | 0.70 | F2 (0.51) | F2KLKB1F10PLGPROC | |
| SCHEMBL20117569 | 0.70 | MASP2 (0.43) | PSMB5NFKB1NFKB2RELAMASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015197309-A1 | PROCESS FOR THE PRODUCTION OF A DIPEPTIDE DERIVATIVE | DSM IP ASSETS B.V. (NL) | 2015-12-30 | — | — | WO | disclosed |