Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 2/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 7/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.39 |
| ▸ | RELA | Q04206 | 5/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20117449 | 0.90 | MASP2 (0.43) | MASP2PSMB5NFKB1NFKB2RELA | |
| SCHEMBL20117568 | 0.88 | F2 (0.49) | MASP2PSMB5NFKB1NFKB2RELA | |
| SCHEMBL20117570 | 0.86 | MASP2 (0.45) | MASP2PSMB5NFKB1NFKB2RELA | |
| SCHEMBL16938447 | 0.85 | MASP2 (0.42) | MASP2PSMB5NFKB1NFKB2RELA | |
| SCHEMBL17381407 | 0.84 | F2 (0.44) | MASP2PSMB5NFKB1NFKB2RELA | |
| SCHEMBL20117685 | 0.79 | PSMB5 (0.42) | MASP2PSMB5NFKB1NFKB2RELA | |
| SCHEMBL20117448 | 0.77 | F2 (0.55) | MASP2PSMB5NFKB1NFKB2RELA | |
| SCHEMBL20117686 | 0.76 | F2 (0.52) | MASP2PSMB5NFKB1NFKB2RELA | |
| SCHEMBL18875515 | 0.75 | F2 (0.45) | MASP2PSMB5NFKB1NFKB2RELA | |
| SCHEMBL17381507 | 0.74 | F2 (0.48) | MASP2PSMB5NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160939-B1 | PROCESS FOR THE PRODUCTION OF A DIPEPTIDE DERIVATIVE | DSM IP ASSETS BV (NL) | 2018-05-02 | — | — | EP | disclosed |