Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 6/20 | 0.77 |
| ▸ | THRB | P10828 | 2/20 | 0.77 |
| ▸ | BLM | P54132 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.77 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.77 |
| ▸ | GABRP | O00591 | 1/20 | 0.77 |
| ▸ | GABRD | O14764 | 1/20 | 0.77 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.77 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.77 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.77 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.77 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.77 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.77 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL2451627 | 1.00 | LMNA (0.77) | LMNATHRBBLMKMT2ANPSR1 | |
| Succinic Acid SCHEMBL8577076 | 0.90 | LMNA (0.83) | LMNATHRBBLMKMT2ANPSR1 | |
| Succinic Acid SCHEMBL8434204 | 0.90 | LMNA (0.83) | LMNATHRBBLMKMT2ANPSR1 | |
| Glutarate SCHEMBL2915734 | 0.90 | LMNA (0.82) | LMNATHRBBLMKMT2ANPSR1 | |
| Glutarate SCHEMBL9453439 | 0.90 | LMNA (0.82) | LMNATHRBBLMKMT2ANPSR1 | |
| Succinic Acid SCHEMBL5376250 | 0.90 | LMNA (0.83) | LMNATHRBBLMKMT2ANPSR1 | |
| Succinic Acid SCHEMBL2450010 | 0.90 | LMNA (0.83) | LMNATHRBBLMKMT2ANPSR1 | |
| Sebacic Acid SCHEMBL5177102 | 0.88 | LMNA (0.89) | LMNATHRBBLMKMT2ANPSR1 | |
| Azelaic Acid SCHEMBL5174893 | 0.88 | LMNA (0.89) | LMNATHRBBLMKMT2ANPSR1 | |
| Gamma-Aminobutyric Acid SCHEMBL3973563 | 0.87 | LMNA (1.00) | LMNATHRBBLMKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080115423-A1 | Polishing Composition For Silicon Wafer | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-05-22 | — | — | US | claimed |
| US-20020039980-A1 | Chelating agent and detergent comprising the same | MITSUBISHI RAYON CO., LTD. | 2002-04-04 | — | — | US | claimed |
| US-20010034318-A1 | Chelating agent and detergent comprising the same | NITTO CHEMICAL INDUSTRY CO., LTD (NAME CHANGED TO MITSUBISHI RAYON CO., LTD.) | 2001-10-25 | — | — | US | claimed |
| EP-0783034-A2 | Chelating agent and detergent comprising the same | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-07-09 | — | — | EP | claimed |
| JP-9049084-A | — | — | None | — | — | JP | disclosed |
| US-20170210983-A1 | METHOD OF MANUFACTURING A FLUORESCENT SUBSTANCE HAVING A MATRIX OF NITRIDE OR OXYNITRIDE, A FLUORESCENT SUBSTANCE MANUFACTURED BY THE ABOVE METHOD, AND LIGHT EMITTING ELEMENT AND DEVICE USING SAME | DYDEN CORP (JP) | 2017-07-27 | — | — | US | disclosed |
| US-9139771-B2 | Copper oxide etchant and etching method using the same | ASAHI KASEI E-MATERIALS CORPORATION (JP) | 2015-09-22 | — | — | US | disclosed |
| CN-101400758-B | Method for producing aluminate phosphor and aluminate phosphor | CHUBU CHELEST CO LTD | 2013-07-17 | — | — | CN | disclosed |
| EP-2159274-B1 | BRAKE FLUID CONTAINING TETRAZOLE | CHIYODA CHEMICAL CO LTD (JP) | 2013-04-17 | — | — | EP | disclosed |
| CN-101688145-B | Functional fluid | CHIYODA CHEMICAL CO LTD | 2013-03-27 | — | — | CN | disclosed |
| US-20130026134-A1 | COPPER OXIDE ETCHANT AND ETCHING METHOD USING THE SAME | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2013-01-31 | — | — | US | disclosed |
| US-8357642-B2 | Functional fluid | CHIYODA CHEMICAL CO., LTD. (JP) | 2013-01-22 | — | — | US | disclosed |
| EP-0783034-A2 | Chelating agent and detergent comprising the same | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |
| JP-H0949084-A | ELECTROLESS COPPER PLATING BATH USING DIAMINE TYPE BIODEGRADABLE CHELATING AGENT | NITTO CHEM IND CO LTD | 1997-02-18 | — | — | JP | disclosed |
| EP-0731171-A2 | Method of producing optically active amino acid | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-09-11 | — | — | EP | disclosed |
| EP-0611990-B1 | A photographic composition having fixing capacity and a method for processing using the same | FUJI PHOTO FILM CO LTD (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5543272-A | USING A MIXTURE OF A THIOSULFONE AND SULFONE COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1996-08-06 | — | — | US | disclosed |
| EP-0694528-A2 | Alkylenediamine-N,N'-disuccinic acid iron (III) complex salts and process for production thereof | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-01-31 | — | — | EP | disclosed |
| US-5460923-A | Containing fixing accelerators | FUJI PHOTO FILM CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0611990-A1 | A photographic composition having fixing capacity and a method for processing using the same | FUJI PHOTO FILM CO., LTD. (JP) | 1994-08-24 | — | — | EP | disclosed |