Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19007302 | 0.84 | ALDH1A1 (0.65) | LMNAGAAALDH1A1PTGDR2APAF1 | |
| SCHEMBL4744968 | 0.79 | ALDH1A1 (0.69) | LMNAGAAALDH1A1MAPTHTT | |
| SCHEMBL17740400 | 0.74 | ADORA2A (0.42) | LMNAGAAALDH1A1MAPTHTT | |
| SCHEMBL19321640 | 0.74 | LMNA (0.45) | LMNAGAAALDH1A1MAPTHTT | |
| SCHEMBL2561808 | 0.74 | LMNA (0.45) | LMNAGAAALDH1A1MAPTHTT | |
| SCHEMBL31000970 | 0.71 | KDM4E (0.35) | LMNAGAAALDH1A1MAPTHTT | |
| SCHEMBL1520529 | 0.71 | POLB (0.63) | LMNAALDH1A1HTTPOLBNPC1 | |
| SCHEMBL16612479 | 0.68 | MAPK1 (0.47) | LMNAGAAALDH1A1MAPTHTT | |
| SCHEMBL24050141 | 0.67 | LMNA (0.40) | LMNAGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL11559781 | 0.67 | TSHR (0.38) | GAAALDH1A1MAPTHTTAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015196759-A1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | TOCOPHERX, INC. (US) | 2015-12-30 | — | — | WO | disclosed |