Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10733772 | 0.80 | GAA (0.47) | KDM4EGAAALDH1A1MAPTADORA2A | |
| SCHEMBL29127378 | 0.79 | SMN1; SMN2 (0.47) | KDM4EGAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL22312633 | 0.79 | KDM4E (0.35) | KDM4EGAAALDH1A1MAPTADORA2A | |
| SCHEMBL10733902 | 0.73 | MAPT (0.56) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL17382016 | 0.71 | LMNA (0.46) | GAAALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL23398958 | 0.71 | ADORA2A (0.39) | KDM4EGAAALDH1A1MAPTADORA2A | |
| SCHEMBL20528971 | 0.71 | ADORA2A (0.39) | KDM4EGAAMAPTADORA2AADORA2B | |
| SCHEMBL31150294 | 0.70 | POLB (0.42) | KDM4EGAAALDH1A1MAPTADORA2A | |
| SCHEMBL7806006 | 0.70 | NPC1 (0.34) | KDM4EGAAALDH1A1MAPTNPC1 | |
| SCHEMBL17740400 | 0.70 | ADORA2A (0.42) | KDM4EGAAALDH1A1MAPTADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118401531-A | Benzimidazole compound and medical application thereof | 中国科学院上海药物研究所 | 2024-07-26 | — | — | CN | disclosed |