SCHEMBL173842

SCHEMBL173842

CCC(OC(=O)OC(CC)C1OC(Oc2nn(C(C)C)c(C)c2Cc2ccc(OC(C)C)cc2)C(O)C(O)C1O)C1OC(Oc2nn(C(C)C)c(C)c2Cc2ccc(OC(C)C)cc2)C(O)C(O)C1O

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 20/20 0.70
SLC5A1 P13866 18/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14634840 1.00 SLC5A2 (0.70) SLC5A2SLC5A1
SCHEMBL14634838 1.00 SLC5A2 (0.70) SLC5A2SLC5A1
SCHEMBL14634839 0.94 SLC5A2 (0.67) SLC5A2SLC5A1
SCHEMBL26892301 0.83 SLC5A2 (0.78) SLC5A2SLC5A1
SCHEMBL14862842 0.83 SLC5A2 (0.80) SLC5A2SLC5A1
SCHEMBL14634764 0.83 SLC5A2 (0.95) SLC5A2SLC5A1
SCHEMBL14634761 0.83 SLC5A2 (0.95) SLC5A2SLC5A1
SCHEMBL877233 0.83 SLC5A2 (0.95) SLC5A2SLC5A1
Remogliflozin Etabonate SCHEMBL23072082 0.82 SLC5A2 (1.00) SLC5A2SLC5A1
Remogliflozin Etabonate SCHEMBL15168697 0.82 SLC5A2 (1.00) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011127051-A1 MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. (US) 2011-10-13 WO claimed
WO-2011127051-A1 MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. (US) 2011-10-13 WO disclosed