Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 3/20 | 0.40 |
| ▸ | ACE | P12821 | 5/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNG | P07510 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRND | Q07001 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16645035 | 0.94 | REN (0.42) | RENACEACE2TSHRATM | |
| SCHEMBL16645016 | 0.89 | REN (0.42) | RENACEACE2TSHRATM | |
| SCHEMBL16645041 | 0.86 | REN (0.44) | RENACEACE2CTSDOPRM1 | |
| SCHEMBL17384262 | 0.86 | REN (0.38) | RENACEACE2ATML3MBTL1 | |
| SCHEMBL16645117 | 0.86 | REN (0.40) | RENACEACE2TSHRATM | |
| SCHEMBL16645207 | 0.86 | REN (0.40) | RENACEACE2TSHRATM | |
| SCHEMBL26536406 | 0.85 | REN (0.40) | RENACEACE2TSHRATM | |
| SCHEMBL16645137 | 0.83 | REN (0.41) | RENACEACE2TSHRATM | |
| SCHEMBL16645063 | 0.82 | REN (0.41) | RENACEACE2TSHRATM | |
| SCHEMBL23656857 | 0.81 | SSTR2 (0.39) | RENACEACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015195925-A1 | PROTEIN-POLYMER-DRUG CONJUGATES AND METHODS OF USING SAME | MERSANA THERAPEUTICS, INC. (US) | 2015-12-23 | — | — | WO | disclosed |