SCHEMBL17384394

SCHEMBL17384394

CN(C)c1ccc(N2COCN(c3ccc(N(C)C)cc3)CN(c3ccc(N(C)C)cc3)C2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.44
ALDH1A1 P00352 12/20 0.43
MAPT P10636 6/20 0.43
TDP1 Q9NUW8 4/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
ALOX15 P16050 3/20 0.43
HSD17B10 Q99714 2/20 0.43
LMNA P02545 2/20 0.43
HTT P42858 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
USP2 O75604 1/20 0.43
POLB P06746 1/20 0.43
HPGD P15428 1/20 0.43
KDM4E B2RXH2 5/20 0.42
GAA P10253 5/20 0.42
NPSR1 Q6W5P4 2/20 0.42
TSHR P16473 3/20 0.42
THRB P10828 1/20 0.40
MEN1 O00255 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16633168 0.88 ALDH1A1 (0.55) SLC2A1ALDH1A1MAPTTDP1L3MBTL1
SCHEMBL16640899 0.84 ALDH1A1 (0.62) SLC2A1ALDH1A1MAPTTDP1L3MBTL1
SCHEMBL19213224 0.78 ALDH1A1 (0.44) SLC2A1ALDH1A1MAPTTDP1L3MBTL1
SCHEMBL18068758 0.77 ALDH1A1 (0.42) SLC2A1ALDH1A1MAPTTDP1L3MBTL1
SCHEMBL19213223 0.77 RELA (0.57) SLC2A1ALDH1A1MAPTALOX15LMNA
SCHEMBL9094196 0.76 SLC2A1 (0.67) SLC2A1ALDH1A1MAPTTDP1L3MBTL1
SCHEMBL17366458 0.76 ALDH1A1 (0.41) SLC2A1ALDH1A1MAPTTDP1L3MBTL1
SCHEMBL2201868 0.71 ALDH1A1 (0.51) SLC2A1ALDH1A1MAPTTDP1L3MBTL1
SCHEMBL30408019 0.71 ALDH1A1 (0.51) SLC2A1ALDH1A1MAPTTDP1L3MBTL1
SCHEMBL9871286 0.70 KDM4E (0.41) SLC2A1ALDH1A1MAPTTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015195686-A1 PREPARATION OF POLY(OCTATRIAZACANE) INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-12-23 WO disclosed