Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9244371 | 0.86 | KDM4E (0.40) | KDM4EGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL16633168 | 0.80 | ALDH1A1 (0.55) | KDM4EGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL9242377 | 0.80 | MAPT (0.55) | KDM4EGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL9240813 | 0.80 | SIGMAR1 (0.53) | ALDH1A1MAPTALOX15HSD17B10DRD3 | |
| SCHEMBL9871503 | 0.78 | KDM4A (0.33) | KDM4EGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL9244927 | 0.74 | DRD2 (0.40) | KDM4EGAAALDH1A1MAPTLMNA | |
| SCHEMBL9241135 | 0.74 | HRH2 (0.43) | KDM4EGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL9241807 | 0.74 | GAA (0.38) | KDM4EGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL16640899 | 0.73 | ALDH1A1 (0.62) | KDM4EGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL9551175 | 0.72 | SIGMAR1 (0.45) | MAPTNPSR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | claimed |