Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TK2 | O00142 | 1/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4316736 | 0.82 | TYMS (0.46) | — | |
| SCHEMBL17384497 | 0.77 | TK1 (0.37) | TK1LMNASMN1; SMN2TK2SLC5A2 | |
| SCHEMBL18870829 | 0.76 | SLC5A2 (0.53) | SLC5A2 | |
| SCHEMBL16631235 | 0.76 | SLC5A2 (0.53) | SLC5A2 | |
| SCHEMBL16781787 | 0.76 | SLC5A2 (0.53) | SLC5A2 | |
| SCHEMBL16805395 | 0.76 | SLC5A2 (0.53) | SLC5A2 | |
| SCHEMBL17082398 | 0.76 | SLC5A2 (0.53) | SLC5A2 | |
| SCHEMBL16781782 | 0.76 | SLC5A2 (0.53) | SLC5A2 | |
| SCHEMBL13947907 | 0.76 | SLC5A2 (0.43) | SLC5A2 | |
| SCHEMBL9634749 | 0.75 | LMNA (0.37) | TK1LMNASMN1; SMN2TK2SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015196118-A1 | ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2015-12-23 | — | — | WO | disclosed |